General
Preferred name
Solanidine
Synonyms
P&D ID
PD167279
CAS
80-78-4
Tags
available
natural product
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 411
DESCRIPTION Solanidine, a cholestane alkaloid isolated from potato species [Solanum spp.], exhibits antitumor effects by inhibiting cell proliferation.
DESCRIPTION Solanidine is a plant-derived steroidal alkaloid compound, that is present in the Solanaceae (potato) family, Fritillaria species, and Veratrum grandiflorum . Its metabolism is being investigated as a method of predicting an individual's CYP2D6 activity . (GtoPdb)
Compound Sets
3
Cayman Chemical Bioactives
36433
Guide to Pharmacology
12500
MedChem Express Bioactive Compound Library
HY-N7271
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
397.33
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
6
Aromatic Ring Count
0
cLogP
5.66
TPSA
23.47
Fraction CSP3
0.93
Chiral centers
11.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
MDM-2/p53
RAD51
Pathway
Apoptosis
Cell Cycle/DNA Damage
Source data