General
Preferred name
CIRSIMARIN
Synonyms
Cirsitakaoside ()
P&D ID
PD166747
CAS
13020-19-4
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Cirsimarin is a potent antilipogenic flavonoid isolated from Microtea debilis. Cirsimarin exerts potent antilipogenic effect and decreases adipose tissue deposition in mice. The lipolytic activity of Cirsimarin resulting from both its antagonist activity on adenosin A1 receptor and its inhibitory effect on phosphodiesterase[1].
PRICE 403
DESCRIPTION Cirsimarin (Cirsitakaoside) is a flavonoid isolated from Microtea debilis. It shows a potent antilipogenic effect and decreases adipose tissue deposition in mice. Cirsimarin has antagonist activity on the adenosine A1 receptor and inhibitory effect on phosphodiesterase. (TargetMol Bioactive Compound Library)
Compound Sets
4
DrugMAP
DMM10TG
MedChem Express Bioactive Compound Library
HY-N7272
Selleckchem Bioactive Compound Library
cirsimarin
TargetMol Bioactive Compound Library
T10822
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
476.13
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
5
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
0.36
TPSA
168.28
Fraction CSP3
0.35
Chiral centers
5.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
A1
Phosphodiesterase (PDE)
PDE
Pathway
GPCR/G protein
Neuroscience
Metabolic Enzyme/Protease
Source data