General
Preferred name
Lupiwighteone
Synonyms
8-prenylgenistein ()
P&D ID
PD166546
CAS
104691-86-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Lupiwighteone is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway[1][2].
PRICE 464
DESCRIPTION Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-N3354
TargetMol Bioactive Compound Library
TN1891
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
338.12
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
4.09
TPSA
90.9
Fraction CSP3
0.15
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
Bcl-2
Caspase
PARP
Pathway
Chromatin/Epigenetic
DNA Damage/DNA Repair
Proteases/Proteasome
Source data