General
Preferred name
Elevenostat
Synonyms
JB3-22 ()
P&D ID
PD166479
CAS
1454902-97-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Elevenostat (JB3-22) is a selective HDAC11 inhibitor with an IC50 of 0.235 ¦ÌM. Elevenostat can induce apoptosis of multiple myeloma cells and has anti-tumor effect. In addition, Elevenostat inhibits the maturation of mouse oocytes[1][2].
PRICE 45
DESCRIPTION Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235???M.
DESCRIPTION Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM. (TargetMol Bioactive Compound Library)
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-145757
TargetMol Bioactive Compound Library
T9745
External IDs
8
Properties
(calculated by RDKit )
Molecular Weight
315.12
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
2.14
TPSA
99.69
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
HDAC11
Apoptosis
Caspase
HDAC
Pathway
Chromatin/Epigenetic
DNA Damage/DNA Repair
Cell Cycle/DNA Damage
Epigenetics
Source data