General
Preferred name
FR054
Synonyms
P&D ID
PD166375
CAS
35954-65-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1].
PRICE 29
DESCRIPTION FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect, inducing a dramatic decrease in cell proliferation and survival in various breast cancer cells. (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-124909A
Selleckchem Bioactive Compound Library
fr054
TargetMol Bioactive Compound Library
T9468
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
329.11
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
0
cLogP
-0.04
TPSA
109.72
Fraction CSP3
0.71
Chiral centers
5.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PGM3
phosphatase
Pathway
Metabolic Enzyme/Protease
Source data