General
Preferred name
RAZPIPADON
Synonyms
(Rac)-Razpipadon ()
PW0464 ()
PF-06669571 ()
PW-0464, (-)- ()
CVL-871 ()
PF06669571 ()
CVL871 ()
P&D ID
PD164788
CAS
1643462-93-4
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Drug indication
Alzheimer disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP)[1].
PRICE
765
DESCRIPTION
PW0464, a nanomolar potent complete G protein-biased ligand, is a noncatechol D1R agonist with an EC50 of 5.8 nM (Gs-cAMP)[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
2
ChEMBL Drugs
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Molecular Weight
389.12
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
3
cLogP
3.15
TPSA
86.21
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Dopamine Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data
