General
Preferred name
Alogabat
Synonyms
RG-7816 ()
RO-7017773 ()
RG7816 ()
RO7017773 ()
P&D ID
PD164662
CAS
2230009-48-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Drug indication
Autism spectrum disorder
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Alogabat (example 8) is a GABAA ¦Á5 receptor positive allosteric modulators (PAMs) (extracted from patent WO2018104419A1)[1].
DESCRIPTION
Alogabat is a potent GABAA receptor positive allosteric modulator.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugBank
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
409.18
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
2.63
TPSA
112.26
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABA Receptor
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
