General
Preferred name
AVOTACICLIB
Synonyms
BEY1107 ()
Avotaciclib (hydrochloride) ()
Avotaciclib (trihydrochloride) ()
BEY1107 (hydrochloride) ()
BEY1107 (trihydrochloride) ()
BEY1107 trihydrochloride ()
Avotaciclib trihydrochloride ()
BEY-1107 ()
CDK1 INHIBITOR BEY1107 ()
P&D ID
PD164251
CAS
1983983-41-0
1983984-01-5
Tags
available
drug candidate
Drug Status
investigational
Max Phase
1.0
Drug indication
pancreatic carcinoma
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Avotaciclib (BEY1107) is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2].
PRICE
308
DESCRIPTION
Avotaciclib (BEY1107) hydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib hydrochloride can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib hydrochloride can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2].
DESCRIPTION
Avotaciclib (BEY1107) trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib trihydrochloride can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib trihydrochloride can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2].
DESCRIPTION
Avotaciclib (BEY1107) is a potent, orally active cyclin-dependent kinase 1 (CDK1) inhibitor, suitable for research in locally advanced or metastatic pancreatic cancer.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
DrugBank
MedChem Express Bioactive Compound Library
PKIDB
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
281.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
3
cLogP
0.87
TPSA
136.72
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CDK1
Apoptosis
CDK
Pathway
Cell Cycle/Checkpoint
Cell Cycle/DNA Damage
Source data
