General
Preferred name
CERONAPRIL
Synonyms
Ceronaprilum ()
SQ 29852 ()
SQ-29852 ()
SQ29852 ()
SQ 29,852 ()
P&D ID
PD162219
CAS
120122-26-1
141743-49-9
111223-26-8
Tags
available
drug candidate
Drug indication
Major depressive disorder
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
ChEMBL Drugs
DrugMAP
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
440.21
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
1
cLogP
2.78
TPSA
130.16
Fraction CSP3
0.62
Chiral centers
3.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ACE
Pathway
Endocrinology/Hormones
Source data
