General
Preferred name
BMS-193884
Synonyms
BMS 193884 ()
P&D ID
PD161039
CAS
176960-47-7
Tags
available
drug candidate
Drug indication
Pulmonary arterial hypertension
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
BMS-193884 is a selective endothelin receptor A (ETA) antagonist . Its clinical pharmacological profile supported progression as a clinical candidate for studies in congestive heart failure.
(GtoPdb)
DESCRIPTION
BMS-193884, an oxazol derivative, has been found to be an endothelin A receptor antagonist and was once studied in the treatmen of heart failure.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
DrugMAP
Guide to Pharmacology
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
9
Molecular Weight
395.09
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
4
cLogP
4.41
TPSA
98.23
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.54
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
