General
Preferred name
RESEQUINIL
Synonyms
Radequinil ()
AC-3933 ()
AVE-3933 ()
SX-3933 ()
Radequinilo ()
P&D ID
PD160338
CAS
219846-31-8
Tags
available
drug candidate
Drug indication
Alzheimer disease
Epilepsy
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1].
Compound Sets
3
ChEMBL Drugs
CHEMBL2107801
DrugMAP
DM3EAYN
MedChem Express Bioactive Compound Library
HY-106025
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
334.11
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
4
cLogP
3.37
TPSA
94.16
Fraction CSP3
0.11
Chiral centers
0.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
GABA Receptor
Source data