General
Preferred name
Angiotensin I/II 1-5
Synonyms
Angiotensin I/II (1-5) (TFA) ()
Angiotensin I/II (1-5) ()
P&D ID
PD159299
CAS
58442-64-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Angiotensin I/II 1-5 TFA is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin I/II 1-5 TFA is an active mediator of renin-angiotensin system to stimulate atrial natriuretic peptide (ANP) secretion via Mas R and PI3K-Akt-NOS pathway.[1][2].
DESCRIPTION Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II. (TargetMol Bioactive Compound Library)
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-P1839A
TargetMol Bioactive Compound Library
TP1528
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
664.35
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
10
Rotatable Bonds
20
Ring Count
1
Aromatic Ring Count
1
cLogP
-1.48
TPSA
301.65
Fraction CSP3
0.57
Chiral centers
6.0
Largest ring
6.0
QED
0.04
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Angiotensin Receptor
Pathway
GPCR/G protein
Endocrinology/Hormones
Source data