General
Preferred name
Takeda103A
Synonyms
CMPD103A ()
Takeda-103A ()
Takeda-103-A ()
CMPD-103A ()
Takeda 103 A ()
P&D ID
PD158814
CAS
865609-72-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Takeda103A is a potent inhibitor of GRK2. G protein-coupled receptors (GPCRs) are central to many physiological processes. Takeda103A has the potential for the research of heart failure[1].
PRICE 255
DESCRIPTION Takeda103A (CMPD103A) is the GRK2-dependent bovine tubulin oxidation effective inhibitor. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
41027
MedChem Express Bioactive Compound Library
HY-129118
TargetMol Bioactive Compound Library
T24850
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
463.19
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
4
cLogP
3.97
TPSA
97.62
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
6.0
QED
0.39
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
GRK2
G Protein-coupled Receptor Kinase (GRK)
Pathway
GPCR/G protein
Source data