General
Preferred name
KARANJIN
Synonyms
P&D ID
PD158715
CAS
521-88-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research[1].
PRICE 103
DESCRIPTION Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis. (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-N2534
Selleckchem Bioactive Compound Library
karanjin
TargetMol Bioactive Compound Library
T2S0820
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
292.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
4
cLogP
4.21
TPSA
52.58
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
AMPK
Apoptosis
Cytochrome P450
NF-κB
phosphatase
Pathway
Chromatin/Epigenetic
PI3K/Akt/mTOR signaling
Epigenetics
Metabolic Enzyme/Protease
PI3K/Akt/mTOR
NF-¦ÊB
Source data