General
Preferred name
MAP4343
Synonyms
P&D ID
PD156810
CAS
511-26-2
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2].
PRICE 59
DESCRIPTION Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of neurons from neurotoxic agents. (TargetMol Bioactive Compound Library)
Compound Sets
1
TargetMol Bioactive Compound Library
T9504
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
330.26
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
5.17
TPSA
26.3
Fraction CSP3
0.86
Chiral centers
7.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
microtubule-associated protein 2
Microtubule/Tubulin
Pathway
Cytoskeletal Signaling
Cell Cycle/DNA Damage
cytoskeleton
Source data