General
Preferred name
ASP2905
Synonyms
ASP-2905 ()
ASP 2905 ()
P&D ID
PD156476
CAS
792184-90-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION ASP2905 is a potent and selective potassium channel Kv12.2 inhibitor encoded by the Kcnh3/BEC1 gene. ASP2905 can cross the blood-brain barrier and has antipsychotic activities[1][2].
PRICE 82
DESCRIPTION ASP-2905 is a potent and selective?inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities
DESCRIPTION ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities (TargetMol Bioactive Compound Library)
Compound Sets
4
Axon Medchem Screening Library
2979
Cayman Chemical Bioactives
40780
MedChem Express Bioactive Compound Library
HY-122015
TargetMol Bioactive Compound Library
T9070
External IDs
8
Properties
(calculated by RDKit )
Molecular Weight
388.16
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
4
cLogP
3.9
TPSA
100.54
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Potassium Channel
Kv12.2
KCNH3 inhibitor
Pathway
Membrane Transporter/Ion Channel
Source data