General
Preferred name
Tesamorelin
Synonyms
Egrifta ()
P&D ID
PD155008
CAS
804475-66-9
Tags
drug
Drug indication
HIV-associated lipodystrophy
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION This drug is a stabilized synthetic peptide analogue of the hypothalamic peptide GHRH. The approved formulation is the acetate salt. The chemical structure shown here was generated using the SMILES from PubChem CID 16137828. (GtoPdb)
Compound Sets
4
DrugMAP
DM9GP85
DrugMAP Approved Drugs
DM9GP85
Guide to Pharmacology
6959
Natural product-based probes and drugs
External IDs
1
Properties
(calculated by RDKit )
Molecular Weight
5132.72
Hydrogen Bond Acceptors
72
Hydrogen Bond Donors
83
Rotatable Bonds
181
Ring Count
3
Aromatic Ring Count
3
cLogP
-27.03
TPSA
2339.37
Fraction CSP3
0.63
Chiral centers
44.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Biosynthetic Origin
Peptide (Ribosomal)
Therapeutic Indication
Lipodystrophy Syndrome
Therapeutic Class
Hormone Therapy
Source data