General
Preferred name
OPIORPHIN
Synonyms
P&D ID
PD154858
CAS
864084-88-8
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Opiorphin is an endogenous pentapeptide. It reduces the breakdown of the natural analgesic enkephalins by acting as an inhibitor of enkephalin-degrading proteases including neutral ecto-endopeptidase (MME; neprilysin), ecto-aminopeptidase N (ANPEP; ANP) and dipeptidyl peptidase DPP3.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
2
Guide to Pharmacology
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
692.37
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
12
Rotatable Bonds
23
Ring Count
1
Aromatic Ring Count
1
cLogP
-5.05
TPSA
371.84
Fraction CSP3
0.52
Chiral centers
5.0
Largest ring
6.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
Neprilysin
Source data
