General
Preferred name
Gentisein
Synonyms
NSC 329491 ()
NSC329491 ()
NSC-329491 ()
1,3,7-Trihydroxyxanthone ()
P&D ID
PD150735
CAS
529-49-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 ¦ÌM[1][2].
PRICE 33
DESCRIPTION Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 ??M[1][2].
DESCRIPTION Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2]. (TargetMol Bioactive Compound Library)
Cell lines
4
Organisms
0
Compound Sets
3
Cayman Chemical Bioactives
33877
MedChem Express Bioactive Compound Library
HY-118166
TargetMol Bioactive Compound Library
T19931
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
244.04
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
3
cLogP
2.06
TPSA
90.9
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
5-HT Receptor
serotonin
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Source data