General
Preferred name
UNIFIRAM
Synonyms
DM232 ()
P&D ID
PD150731
CAS
272786-64-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Unifiram (DM232) is acts as a potent cognition enhancer?through the activation of the AMPA-mediated neurotransmission system. Unifiram (DM232) has the potential for amnesia prevention and neurodegenerative disorder research[1][2].
PRICE 29
DESCRIPTION Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
34209
MedChem Express Bioactive Compound Library
HY-125931
TargetMol Bioactive Compound Library
T38192
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
298.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
1
cLogP
0.82
TPSA
57.69
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.81
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
iGluR
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data