General
Preferred name
CHRYSOERIOL
Synonyms
P&D ID
PD150718
CAS
491-71-4
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, I¦ÊB/p65, and NF-¦ÊB pathways, and has strong anti-inflammatory activity[1][2][3].
PRICE 128
DESCRIPTION Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect. (TargetMol Bioactive Compound Library)
Cell lines
3
Organisms
0
Compound Sets
6
Cayman Chemical Bioactives
33395
DrugBank
DB17283
DrugMAP
DM96ECL
MedChem Express Bioactive Compound Library
HY-121471
Selleckchem Bioactive Compound Library
chrysoeriol
TargetMol Bioactive Compound Library
TN1490
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
300.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
3
cLogP
2.59
TPSA
100.13
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Akt
ERK
p38
JAK2/STAT3, NF-¦ÊB
Pathway
Metabolic Enzyme/Protease
Cytoskeletal Signaling
MAPK
PI3K/Akt/mTOR signaling
Source data