General
Preferred name
ALC-0315
Synonyms
DSRM-3716 ()
ALC-0315 (Excipient) ()
P&D ID
PD150593
CAS
2036272-55-4
58142-99-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine[1].
DESCRIPTION ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine[1].
PRICE 103
DESCRIPTION ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine
Compound Sets
3
Cayman Chemical Bioactives
39517
34337
MedChem Express Bioactive Compound Library
HY-138170
Selleckchem Bioactive Compound Library
alc-0315
External IDs
7
Properties
(calculated by RDKit )
Molecular Weight
765.72
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
44
Ring Count
0
Aromatic Ring Count
0
cLogP
13.94
TPSA
76.07
Fraction CSP3
0.96
Chiral centers
2.0
Largest ring
0.0
QED
0.05
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Liposome
SARS-CoV
Pathway
Anti-infection
Metabolic Enzyme/Protease
Source data