General
Preferred name
LADOSTIGIL
Synonyms
Ladostigil (hydrochloride) ()
Ladostigil tartrate ()
TV-3326 (hydrochloride) ()
TV-3326 FREE BASE ()
TV-3326 ()
P&D ID
PD143697
CAS
209394-27-4
209394-18-3
Tags
available
drug candidate
covalent binder
Drug indication
Alzheimer disease
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
CovalentInDB
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
272.15
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
2.35
TPSA
41.57
Fraction CSP3
0.44
Chiral centers
1.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuronal Signaling
Target
Cholinesterase (ChE)
Monoamine Oxidase
Source data
