General
Preferred name
NOLASIBAN
Synonyms
Erlosiban ()
OBE-001 ()
Obe001 ()
P&D ID
PD143679
CAS
1477482-19-1
Tags
drug candidate
Drug Status
investigational
Max Phase
3.0
Drug indication
Infertility
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugBank
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
8
Molecular Weight
338.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
2.87
TPSA
62.13
Fraction CSP3
0.3
Chiral centers
1.0
Largest ring
6.0
QED
0.87
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
