General
Preferred name
PD143477
Synonyms
2'-O-Methylcytidine ()
2′-O-Methylcytidine ()
2??-O-Methylcytidine ()
P&D ID
PD143477
CAS
2140-72-9
35819-07-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION 2??-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate. 2??-O-Methylcytidine inhibits HCV RNA replication.
DESCRIPTION 2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate. 2′-O-Methylcytidine inhibits HCV RNA replication. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
3
Cayman Chemical Bioactives
33411
MedChem Express Bioactive Compound Library
HY-W011834
TargetMol Bioactive Compound Library
T38237
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
257.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
1
cLogP
-1.91
TPSA
119.83
Fraction CSP3
0.6
Chiral centers
4.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HCV
Nucleoside antimetabolite/analog
DNA/RNA Synthesis
Pathway
Anti-infection
Cell Cycle/DNA Damage
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Microbiology/virology
Proteases/Proteasome
Source data