General
Preferred name
CEFAZAFLUR
Synonyms
CEFAZAFLUR SODIUM ()
SK&F 59962 ()
P&D ID
PD131888
CAS
58665-96-6
52123-49-6
Tags
drug candidate
natural product
available
Drug indication
Antibacterial
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Cefazaflur (SK&F 59962) is a semisynthetic first generation cephalosporin antibacterial . It did not progress beyond preclinical development. Cefazaflur binds to and inactivates penicillin-binding proteins (PBPs) and thereby disrupts normal bacterial cell wall assembly.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
470.01
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
1
cLogP
0.29
TPSA
130.31
Fraction CSP3
0.54
Chiral centers
2.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
