General
Preferred name
H-Tyr-Tyr-OH
Synonyms
L-Tyrosyl-L-tyrosine ()
P&D ID
PD127670
CAS
1050-28-8
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
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[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme (ACE) with an IC50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure[1][2].
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[[ compound.targets[tid].gene_name ]]
Compound Sets
3
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
344.14
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
5
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
0.78
TPSA
132.88
Fraction CSP3
0.22
Chiral centers
2.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Angiotensin-converting Enzyme (ACE)
Member status
virtual
MOA
NPY2R agonist
Pathway
Metabolic Enzyme/Protease
Source data
