General
Preferred name
PD127426
Synonyms
4-Methylamino antipyrine ()
4-Methylaminoantipyrine (hydrochloride) ()
P&D ID
PD127426
CAS
519-98-2
856307-27-2
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].
PRICE 29
DESCRIPTION 4-Methylamino antipyrine, an active metabolite of Metamizole, a pyrazolone non-steroidal anti-inflammatory drug (NSAID) that inhibits COX, possesses analgesic, antipyretic, and relatively weak anti-inflammatory properties. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
31612
MedChem Express Bioactive Compound Library
HY-135731
TargetMol Bioactive Compound Library
T10152
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
217.12
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
1.53
TPSA
38.96
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
COX
Drug Metabolite
Pathway
Immunology/Inflammation
Metabolism
Neuroscience
Metabolic Enzyme/Protease
Source data