General
Preferred name
TRICIN
Synonyms
4', 5, 7-trihydroxy-3', 5'-dimethoxyflavone ()
P&D ID
PD127335
CAS
520-32-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tricin is a natural flavonoid found in large amounts in wheat. Tricin inhibits HCMV replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells by upregulating the expression of FAK-targeting microRNA-7 [1][2][3][1][2][3][4][5].
PRICE 148
DESCRIPTION Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7. (TargetMol Bioactive Compound Library)
Cell lines
2
Organisms
0
Compound Sets
4
Cayman Chemical Bioactives
35835
MedChem Express Bioactive Compound Library
HY-N1127
Selleckchem Bioactive Compound Library
tricin
TargetMol Bioactive Compound Library
TN1068
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
330.07
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
2.59
TPSA
109.36
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
CDK9
CMV
Influenza Virus, CMV, CDK, TNF-alpha, Antioxidant, Antiviral
Pathway
Cell Cycle/Checkpoint
Anti-infection
Source data