General
Preferred name
paederosidic acid methyl ester
Synonyms
P&D ID
PD127273
CAS
122413-01-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Paederosidic acid methyl ester is a ATP©\sensitive K+ channel activator, isolated from P.?scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP©\sensitive K+ channel in the brain and spinal cord level[1].
PRICE 197
DESCRIPTION Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-N2433
Selleckchem Bioactive Compound Library
paederosidic-acid-methyl-ester
External IDs
9
Properties
(calculated by RDKit )
Molecular Weight
478.11
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
5
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
0
cLogP
-1.75
TPSA
181.44
Fraction CSP3
0.68
Chiral centers
9.0
Largest ring
6.0
QED
0.21
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Potassium Channel
K+ channels
Pathway
Membrane Transporter/Ion Channel
Source data