General
Preferred name
TOPTERONE
Synonyms
Topterona ()
WIN-17665 ()
Win 17665 ()
P&D ID
PD127108
CAS
60607-35-4
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
32
DESCRIPTION
Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in castrated immature male hamsters.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
1
ChEMBL Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
330.26
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
5.05
TPSA
37.3
Fraction CSP3
0.86
Chiral centers
6.0
Largest ring
6.0
QED
0.77
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Androgen Receptor
Source data
