General
Preferred name
MALABARICONE B
Synonyms
P&D ID
PD126480
CAS
63335-24-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Malabaricone B, a naturally occurring plant phenolic, is an orally active ¦Á-glucosidase inhibitor with an IC50 of 63.7 ¦ÌM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].
PRICE 281
DESCRIPTION Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
3
Cayman Chemical Bioactives
29911
MedChem Express Bioactive Compound Library
HY-N8517
TargetMol Bioactive Compound Library
TN6771
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
342.18
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
10
Ring Count
2
Aromatic Ring Count
2
cLogP
4.96
TPSA
77.76
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
Glycosidase
Pathway
Metabolic Enzyme/Protease
Source data