General
Preferred name
PDGFRα kinase inhibitor 1
Synonyms
PDGFR¦Á kinase inhibitor 1 ()
P&D ID
PD126261
CAS
2209053-93-8
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
PDGFR¦Á kinase inhibitor 1 is a highly selective type II PDGFR¦Á kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFR¦Á and PDGFR¦Â, respectively[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
1
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
7
Molecular Weight
586.28
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
5
Aromatic Ring Count
5
cLogP
5.44
TPSA
116.24
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.21
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Protein Tyrosine Kinase/RTK
Target
PDGFR
Source data
