General
Preferred name
SBI-553
Synonyms
P&D ID
PD126123
CAS
1849603-72-0
Tags
biased GPCR ligand
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 ¦ÌM[1][2].
PRICE
161
DESCRIPTION
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 ??M).
DESCRIPTION
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
8
Molecular Weight
450.24
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
3
cLogP
4.41
TPSA
61.72
Fraction CSP3
0.46
Chiral centers
0.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Neurotensin Receptor
NTR1
Pathway
GPCR/G protein
Neuronal Signaling
Source data
