General
Preferred name
ISOSCHAFTOSIDE
Synonyms
P&D ID
PD125721
CAS
52012-29-0
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, can inhibit the growth of germinated S. hermonthica radicles. Isoschaftoside reduces reactive oxygen species (ROS) and induces proliferation in senescent cells. Isoschaftoside activates autophagy. Isoschaftoside can be used for anti-tumor, anti-inflammatory, antioxidant, antihypertensive, hepatoprotective and nematicidal study[1][2][3][4][5][6].
PRICE
172
DESCRIPTION
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
564.15
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
10
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
3
cLogP
-1.75
TPSA
250.97
Fraction CSP3
0.42
Chiral centers
9.0
Largest ring
6.0
QED
0.17
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
NF-¦ÊB
Target
Autophagy
p62
Parasite
Reactive Oxygen Species (ROS)
HIF-1¦Á, ERK1/2, mTOR
Reactive Oxygen Species
Fungal
Source data
