General
Preferred name
Brevifolincarboxylic acid
Synonyms
Brevifolincarboxylic Acid ()
P&D ID
PD125566
CAS
18490-95-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Brevifolincarboxylic acid is a phenolic compound. Brevifolincarboxylic acid can be isolated from Duchesnea chrysantha. Brevifolincarboxylic acid inhibits ¦Á-glucosidase with an IC50 value of 323.46 ¦ÌM. Brevifolincarboxylic acid has an inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarbacid scavenges ROS. Brevifolincarbacid restores the glucose uptake activity of myotubes. Brevifolincarboxylic acid has antitumor activity against lung and gastric cancer. Brevifolincarbacid can be used in the study of diabetes and inflammatory diseases[1][2][3][4][5][6].
PRICE 184
DESCRIPTION Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an ??-glucosidase inhibitor with an IC50 of 323.46 ??M.
DESCRIPTION Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 323.46 μM. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
34922
MedChem Express Bioactive Compound Library
HY-N4095
TargetMol Bioactive Compound Library
TN1451
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
292.02
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
4
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
0.66
TPSA
145.27
Fraction CSP3
0.15
Chiral centers
1.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
AHR
Aryl hydrocarbon receptor
α-glucosidase
GLUT
Glycosidase
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
Pathway
Immunology/Inflammation
Metabolism
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
NF-κB
NF-¦ÊB
Source data