General
Preferred name
Pennogenin 3-O-beta-chacotrioside
Synonyms
P&D ID
PD125337
CAS
55916-52-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity[1].
PRICE 269
DESCRIPTION Pennogenin 3-O-beta-chacotrioside, isolated from *Paris polyphylla*, exhibits anti-colorectal cancer activity by modulating autophagy through increased expression of autophagy-related proteins LC3 and Beclin-1. (TargetMol Bioactive Compound Library)
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-N4180
TargetMol Bioactive Compound Library
T8166
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
884.48
Hydrogen Bond Acceptors
17
Hydrogen Bond Donors
9
Rotatable Bonds
7
Ring Count
9
Aromatic Ring Count
0
cLogP
0.36
TPSA
255.91
Fraction CSP3
0.96
Chiral centers
26.0
Largest ring
6.0
QED
0.16
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Autophagy
Target
Atg8/LC3
Source data