General
Preferred name
Licoflavone C
Synonyms
4',5,7-Trihydroxy-8-prenylflavone ()
8-prenylapigenin ()
P&D ID
PD125333
CAS
72357-31-4
Tags
available
probe
drug candidate
Drug indication
Discovery agent
Probe info
Probe type
P&D approved
calculated probe
Probe selectivity
protein-selective
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
9
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Licoflavone C is a prenyl-flavone extracted from Genista ephedroides, reduces the genotoxicity of cancer agents in human peripheral lymphocytes[1].
PRICE
142
DESCRIPTION
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a protective effect against DAU or MMC-induced chromosome damage in cultured human peripheral lymphocytes. Licoflavone C can be used to study fungal infections.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
5
Cayman Chemical Bioactives
DrugMAP
MedChem Express Bioactive Compound Library
Probe Miner (suitable probes)
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
338.12
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
4.09
TPSA
90.9
Fraction CSP3
0.15
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
oxidation-reduction
Target
Fungal
antioxidant
Source data
