General
Preferred name
Kahweol
Synonyms
P&D ID
PD125158
CAS
6894-43-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 138
DESCRIPTION Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity. (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-N6258
Selleckchem Bioactive Compound Library
kahweol
TargetMol Bioactive Compound Library
TN1828
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
314.19
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
5
Aromatic Ring Count
1
cLogP
3.72
TPSA
53.6
Fraction CSP3
0.7
Chiral centers
6.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AMPK
Apoptosis
NF-κB
STAT, TGF-beta/Smad, ERK, JNK
Pathway
Chromatin/Epigenetic
PI3K/Akt/mTOR signaling
Epigenetics
PI3K/Akt/mTOR
Source data