General
Preferred name
Dimethyl lithospermate B
Synonyms
dmLSB ()
P&D ID
PD125069
CAS
875313-64-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist. Dimethyl lithospermate B slows inactivation of sodium current (INa), leading to increased inward current during the early phases of the action potential (AP)[1][2].
PRICE 806
DESCRIPTION Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist. (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-N6868
Selleckchem Bioactive Compound Library
dimethyl-lithospermate-b
TargetMol Bioactive Compound Library
T8299
External IDs
8
Properties
(calculated by RDKit )
Molecular Weight
746.18
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
7
Rotatable Bonds
12
Ring Count
5
Aromatic Ring Count
4
cLogP
3.51
TPSA
256.04
Fraction CSP3
0.21
Chiral centers
4.0
Largest ring
6.0
QED
0.05
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Sodium Channel
Na? channel
Pathway
Membrane Transporter/Ion Channel
Source data