General
Preferred name
[8]-Shogaol
Synonyms
8-SHOGAOL ()
P&D ID
PD124430
CAS
36700-45-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION [8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC50=5 ¦ÌM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC50=17.5 ¦ÌM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC50=5 ¦ÌM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA)[1][2][3][4].
PRICE 253
DESCRIPTION [8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor. (TargetMol Bioactive Compound Library)
Compound Sets
4
Cayman Chemical Bioactives
40273
MedChem Express Bioactive Compound Library
HY-N2435
Selleckchem Bioactive Compound Library
8-shogaol
TargetMol Bioactive Compound Library
T5430
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
304.2
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
11
Ring Count
1
Aromatic Ring Count
1
cLogP
4.82
TPSA
46.53
Fraction CSP3
0.53
Chiral centers
0.0
Largest ring
6.0
QED
0.47
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
COX
COX-2
Pathway
Immunology/Inflammation
Neuroscience
Source data