General
Preferred name
PD124371
Synonyms
2'-acetylacteoside ()
P&D ID
PD124371
CAS
94492-24-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 244
DESCRIPTION 2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 ??M. 2'-Acetylacteoside shows antiproliferative effects on aortic smooth muscle, indicates that it may have preventative effects on arteriosclerosis. 2'-Acetylacteoside (0.071 uM) demonstrates potent rat lens aldose reductase inhibitory activity.
DESCRIPTION 2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smooth muscle, indicates that it may have preventative effects on arteriosclerosis. 2'-Acetylacteoside (0.071 uM) demonstrates potent rat lens aldose reductase inhibitory activity. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
36511
Selleckchem Bioactive Compound Library
2-acetylacteoside
TargetMol Bioactive Compound Library
T6102
External IDs
9
Properties
(calculated by RDKit )
Molecular Weight
666.22
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
8
Rotatable Bonds
11
Ring Count
4
Aromatic Ring Count
2
cLogP
-0.45
TPSA
251.36
Fraction CSP3
0.48
Chiral centers
10.0
Largest ring
6.0
QED
0.09
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Aldose Reductase
antioxidant
RANKL/RANK/TRAF6
MOA
Reductase inhibitor
Antioxidant
Pathway
Endocrinology/Hormones
Metabolism
oxidation-reduction
Source data