General
Preferred name
DEHYDROABIETIC ACID
Synonyms
Dehydroabietate ()
DAA, DHAA ()
P&D ID
PD124324
CAS
1740-19-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-¦Á/¦Ã agonist and PPAR-¦Ã partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice[1][2].
PRICE 63
DESCRIPTION 1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models. (TargetMol Bioactive Compound Library)
Cell lines
10
Organisms
0
Compound Sets
4
Cayman Chemical Bioactives
33722
MedChem Express Bioactive Compound Library
HY-N6869
Selleckchem Bioactive Compound Library
dehydroabietic-acid
TargetMol Bioactive Compound Library
TCS1772
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
300.21
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
1
cLogP
4.9
TPSA
37.3
Fraction CSP3
0.65
Chiral centers
3.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
EBV
antibiotic
Bacterial
Fungal
PPAR
Anti-infection,Src,Syk,TAK1
MOA
Antifection
Pathway
Microbiology/virology
Anti-infection
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data