General
Preferred name
Tenofovir exalidex
Synonyms
CMX-157 ()
CMX157 ()
Hexadecyloxypropyl Tenofovir ()
Hdp-tenofovir ()
P&D ID
PD122117
CAS
911208-73-6
Tags
available
drug candidate
Drug indication
Human immunodeficiency virus infection
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
3
Compound Sets
5
ChEMBL Drugs
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
569.37
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
2
Rotatable Bonds
25
Ring Count
2
Aromatic Ring Count
2
cLogP
6.86
TPSA
134.61
Fraction CSP3
0.82
Chiral centers
2.0
Largest ring
6.0
QED
0.1
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Anti-infection
Cell Cycle/DNA Damage
Target
HBV
HIV
Nucleoside antimetabolite/analog
Source data
