General
Preferred name
Ezetimibe-glucuronide
Synonyms
Ezetimibe phenoxy glucuronide ()
Ezetimibe glucuronide ()
Ezetimibe β-D-glucuronide ()
Ezetimibe ¦Â-D-glucuronide ()
P&D ID
PD121435
CAS
190448-57-8
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
585.18
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
5
Rotatable Bonds
9
Ring Count
5
Aromatic Ring Count
3
cLogP
2.45
TPSA
156.99
Fraction CSP3
0.33
Chiral centers
8.0
Largest ring
6.0
QED
0.24
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Drug Metabolite
Pathway
Metabolic Enzyme/Protease
Source data
