General
Preferred name
GINSENOSIDE RH2
Synonyms
(20R)Ginsenoside Rh2 ()
20(R)-Ginsenoside Rh2 ()
P&D ID
PD119967
CAS
112246-15-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity[1][2][3]. 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 ¦ÌM for murine MHV-68[4].
PRICE 160
DESCRIPTION 20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
27300
MedChem Express Bioactive Compound Library
HY-N1401
TargetMol Bioactive Compound Library
T3813
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
622.44
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
6
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
0
cLogP
4.32
TPSA
139.84
Fraction CSP3
0.94
Chiral centers
15.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Microbiology/virology
Proteases/Proteasome
Anti-infection
Cell Cycle/DNA Damage
GPCR/G protein
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
PI3K/Akt/mTOR
Target
Akt
DNA/RNA Synthesis
HSV
MMP
NO Synthase
Prostaglandin Receptor
Reactive Oxygen Species (ROS)
Source data