General
Preferred name
AFZELIN
Synonyms
Kaempferol-3-O-rhamnoside ()
Kaempferol 3-rhamnoside ()
P&D ID
PD118106
CAS
482-39-3
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin[1][2][3][4].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
3
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
432.11
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
6
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
0.78
TPSA
170.05
Fraction CSP3
0.29
Chiral centers
5.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Autophagy
Bacterial
Mitochondrial Metabolism
PTEN
Bcl-2
Pathway
Anti-infection
Metabolic Enzyme/Protease
PI3K/Akt/mTOR
Source data
