General
Preferred name
Leriglitazone
Synonyms
Hydroxypioglitazone ()
Leriglitazone (hydrochloride) ()
LERIGLITAZONE HYDROCHLORIDE ()
MIN-102 (hydrochloride) ()
Hydroxypioglitazone (hydrochloride) ()
MIN-102 HCl ()
Hydroxypioglitazone hydrochloride ()
MIN-102 ()
Hydroxy Pioglitazone ()
P&D ID
PD117467
CAS
146062-44-4
146062-46-6
Tags
drug candidate
natural product
available
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
372.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
2
cLogP
2.65
TPSA
88.52
Fraction CSP3
0.32
Chiral centers
2.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PPAR? agonist
PPAR
Pathway
Cell Cycle/DNA Damage
Vitamin D Related/Nuclear Receptor
Source data
