General
Preferred name
CL-323509
Synonyms
1-Cinnamoylpyrrolidine ()
P&D ID
PD115681
CAS
52438-21-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 239
DESCRIPTION 1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolidine inhibits PAF-induced platelet aggregation with an IC50 value of 37.3 ??M. value was 37.3 ??M.
DESCRIPTION 1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolidine inhibits PAF-induced platelet aggregation with an IC50 value of 37.3 μM. value was 37.3 μM. (TargetMol Bioactive Compound Library)
Compound Sets
2
Cayman Chemical Bioactives
36483
TargetMol Bioactive Compound Library
TN1170
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
201.12
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
2.32
TPSA
20.31
Fraction CSP3
0.31
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
platelet-activating factor (PAF)
DNA Stain
Pathway
Cell Cycle/DNA Damage
Source data