General
Preferred name
Monepantel
Synonyms
AAD1566 ()
PPL-1 ()
Monepantel component of zolvix ()
Zolvix ()
P&D ID
PD101563
CAS
887148-69-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
1.0
Drug indication
motor neuron disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
PRICE
365
DESCRIPTION
Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
2
Compound Sets
5
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
473.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
2
cLogP
5.28
TPSA
85.91
Fraction CSP3
0.25
Chiral centers
1.0
Largest ring
6.0
QED
0.46
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
nAChR
MOA
mTOR inhibitor
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
